The Effect of Green Tea Extract (Camellia Sinensis) on the Number of Ovarian Follicles of Female White Rat (Rattus Norvegicus) Exposed to MSG (Monosodium Glutamate): A Literature Review

Abstract

This literature review aims to determine the effect of green tea extract on the number of ovarian follicles of female rats exposed to MSG. The journals studied in this literature review included 10 journals published in 2012-2022 and discussed the effect of green tea on the number of ovarian follicles of female rats exposed to MSG. Of the 10 journals studied, 5 journals stated that giving antioxidants (green tea, vitamin C, Dooshivishari, Chlorella vulgaris and Spirulina platensis) can increase the number of ovarian follicles. There is 1 journal stating that MSG administration can significantly reduce the number of ovarian follicles and if antioxidants (green tea) are given, the reduction in the number of follicles becomes insignificant. As many as 2 journals stated that MSG administration could reduce the number of ovarian follicles while 1 journal stated that MSG administration could increase the number of ovarian follicles in rats without any antioxidant administration. There is also 1 journal stating that MSG can increase follicle atresia and after being given an antioxidant (Ceratonia siliqua) there is a decrease in follicle atresia. Overall it can be concluded that the administration of antioxidants (green tea, vitamin C, Ceratonia siliqua, Dooshivishari, Chlorella vulgaris and Spirulina platensis) can increase the number of ovarian follicles in rats exposed to MSG because antioxidants can neutralize free radicals and the adverse effects resulting from MSG.