Effect of Green Tea Extract (Camellia Sinensis) on MDA Levels of White Rat (Rattus Norvegicus) Ovary Exposed to MSG (Monosodium Glutamate): A Literature Review

Abstract

This literature review aims to determine the effect of green tea extract on ovarian MDA levels exposed to MSG in white rats. The journals studied in this literature review are 10 journals published in 2010-2020 and discuss the effect of exposure to MSG on rat ovaries and treated with antioxidants (Green Tea, Vit C&E, etc.). Results: Of the 10 journals studied, there were 5 journals which said that giving MSG exposure to female rats would increase ovarian and uterine MDA levels. In 5 other journals the results showed that MSG exposure could cause hypertrophy, atrophy, degenerative changes, and changes in the diameter of the follicles, as well as changes in ovarian histology. Exposure to antioxidants (green tea, vitamin C and vitamin E, aloe vera, chorella vulgaris and spirulina plaatensis) shows good results for repairing histological changes in the ovaries and serves to prevent increased levels of MDA in ovaries that have been exposed to MSG because antioxidants are effective in reducing oxidative effects. stress from MSG exposure in rats that have been exposed to MSG.